University of California San Francisco

Publications

  1. Label-free single-vesicle based surface enhanced Raman spectroscopy: A robust approach for investigating the biomolecular composition of small extracellular vesicles.
    Liu Z, Ng M, Srivastava S, Li T, Liu J, Phu TA, Mateescu B, Wang YT, Tsai CF, Liu T, Raffai RL, Xie YH
    PLoS One. 2024; 19(6):e0305418.; 
    PubMed
  2. Extracellular Vesicles at the Helm: Steering the Pathogenesis and Treatment of Atherosclerosis.
    Raffai RL
    Arterioscler Thromb Vasc Biol. 2025 Jul; 45(7):1306-1309.; 
    PubMed
  3. UCSF Research Profile ">Abstract A046: nSMase2-generated ceramide promotes PDA aggression through exosome reprogramming of the stroma.
    Audrey M. Hendley, Atsushi Urano, Xianlu L. Peng, Sudipta Ashe, Tuan A. Phu, Martin Ng, Natanya R. Kerper, David I. Berrios, Jonghyun Lee, David Jin, Gun H. Jang, Oghenekevwe M. Gbenedio, Jeroen P. Roose, Jen J. Yeh, Steven Gallinger, Andrew V. Biankin, Vasilis Ntranos, David K. Chang, David W. Dawson, Grace E. Kim, Valerie M. Weaver, Robert L. Raffai, Matthias Hebrok
    Cancer Research. 2024 Jan 16; 84(2_Supplement):a046-a046.; 
    UCSF Research Profile ">UCSF Research Profile
  4. UCSF Research Profile ">Abstract A066: nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer.
    Audrey M Hendley, Sudipta Ashe, Atsushi Urano, Martin Ng, Tuan A Phu, Xianlu Laura Peng, Changfei Luan, Anna-Marie Finger, Gun Ho Jang, Natanya R Kerper, David I Berrios, David Jin, Jonghyun Lee, Irene R Riahi, Oghenekevwe M Gbenedio, Christina Chung, Jeroen P Roose, Jen Jen Yeh, Steven Gallinger, Andrew V Biankin, Grainne M O’Kane, Vasilis Ntranos, David K Chang, David W Dawson, Grace E Kim, Valerie M Weaver, Robert L Raffai, Matthias Hebrok
    Cancer Research. 2024 Sep 15; 84(17_Supplement_2):a066-a066.; 
    UCSF Research Profile ">UCSF Research Profile
  5. UCSF Research Profile ">Abstract 3047: Extracellular Vesicles Produced By IL4-polarized Human Macrophages Suppress Atherosclerosis By Reprograming Ly6c hi Monocytes.
    Robert L Raffai, Ngan K Vu, Tuan Anh Phu, Martin Ng, Alex Gao
    Arteriosclerosis Thrombosis and Vascular Biology. 2024 May 1; 44(Suppl_1).; 
    UCSF Research Profile ">UCSF Research Profile
  6. nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer.
    Hendley AM, Ashe S, Urano A, Ng M, Phu TA, Peng XL, Luan C, Finger AM, Jang GH, Kerper NR, Berrios DI, Jin D, Lee J, Riahi IR, Gbenedio OM, Chung C, Roose JP, Yeh JJ, Gallinger S, Biankin AV, O'Kane GM, Ntranos V, Chang DK, Dawson DW, Kim GE, Weaver VM, Raffai RL, Hebrok M
    bioRxiv. 2024 Sep 25.; 
    PubMed
  7. Comparison of EV characterization by commercial high-sensitivity flow cytometers and a custom single-molecule flow cytometer.
    Kim J, Xu S, Jung SR, Nguyen A, Cheng Y, Zhao M, Fujimoto BS, Nelson W, Schiro P, Franklin JL, Higginbotham JN, Coffey RJ, Shi M, Vojtech LN, Hladik F, Tewari M, Tigges J, Ghiran I, Jovanovic-Talisman T, Laurent LC, Das S, Gololobova O, Witwer KW, Xu T, Charest A, Jensen KVK, Raffai RL, Jones JC, Welsh JA, Nolan JP, Chiu DT
    J Extracell Vesicles. 2024 Aug; 13(8):e12498.; 
    PubMed
  8. M2 macrophage exosomes reverse heart failure post-myocardial infarction by suppressing type 1 interferon signaling in myeloid cells.
    Ng M, Gao AS, Phu TA, Vu NK, Raffai RL
    Mol Ther. 2026 Jan 07; 34(1):494-510.; 
    PubMed
  9. The EV antibody database: An interactive database of curated antibodies for extracellular vesicle and nanoparticle research.
    Morey A, Ng M, Spanos M, Zhang P, Xu T, Cheung W, Chatterjee E, Gokulnath P, Carnel-Amar N, Soares Chiaretti AL, Nelson C, George J, Luo M, Chakraborty A, Perucci L, Jones JC, Hoff P, Franklin JL, Raffai RL, Das S, Routenberg DA, Nolan JP, Charest A, Laurent LC, Alexander RP
    Extracell Vesicle. 2024 Jun; 3.; 
    PubMed
  10. M2 Macrophage Exosomes Reverse Cardiac Functional Decline in Mice with Diet-Induced Myocardial Infarction by Suppressing Type 1 Interferon Signaling in Myeloid Cells.
    Ng M, Gao AS, Phu TA, Vu NK, Raffai RL
    bioRxiv. 2024 Sep 19.; 
    PubMed