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- Comparison of EV characterization by commercial high-sensitivity flow cytometers and a custom single-molecule flow cytometer.
2024 | PubMed
- Label-free single-vesicle based surface enhanced Raman spectroscopy: A robust approach for investigating the biomolecular composition of small extracellular vesicles.
2024 | PubMed
- Abstract 3047: Extracellular Vesicles Produced By IL4-polarized Human Macrophages Suppress Atherosclerosis By Reprograming Ly6c hi Monocytes.
2024 | PubMed
- The EV antibody database: An interactive database of curated antibodies for extracellular vesicle and nanoparticle research.
2024 | PubMed
- Abstract A046: nSMase2-generated ceramide promotes PDA aggression through exosome reprogramming of the stroma.
2024 | PubMed
- Exomap1 mouse: A transgenic model for in vivo studies of exosome biology.
2023 | PubMed
- Polarized macrophages regulate fibro/adipogenic progenitor (FAP) adipogenesis through exosomes.
2023 | PubMed
- ApoE enhances mitochondrial metabolism via microRNA-142a/146a-regulated circuits that suppress hematopoiesis and inflammation in hyperlipidemia.
2023 | PubMed
- Abstract P3167: Identification Of Macrophage-specific Markers On Extracellular Vesicles In A Transgenic Mouse Model And Humans.
2023 | PubMed
- ApoE expression in macrophages communicates immunometabolic signaling that controls hyperlipidemia-driven hematopoiesis & inflammation via extracellular vesicles.
2023 | PubMed
- Exomap1 mouse: a transgenic model for in vivo studies of exosome biology.
2023 | PubMed
- exRNA-eCLIP intersection analysis reveals a map of extracellular RNA binding proteins and associated RNAs across major human biofluids and carriers.
2023 | PubMed
- Patients with abdominal aortic aneurysms have reduced levels of microRNA 122-5p in circulating exosomes.
2023 | PubMed
- Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases.
2023 | PubMed
- MetfOrmin BenefIts Lower Extremities with Intermittent Claudication (MOBILE IC): randomized clinical trial protocol.
2023 | PubMed
- Abstract C051: Ceramide signaling regulates PDA aggression through exosome reprogramming of the stroma.
2022 | PubMed
- Poster 155: Muscle-Derived Beige Adipose Precursors Secrete Promyogenic Exosomes that Treat Rotator Cuff Muscle Degeneration in Mice and are Identified in Humans by Single-Cell RNA Sequencing.
2022 | PubMed
- Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research.
2022 | PubMed
- Muscle-Derived Beige Adipose Precursors Secrete Promyogenic Exosomes That Treat Rotator Cuff Muscle Degeneration in Mice and Are Identified in Humans by Single-Cell RNA Sequencing.
2022 | PubMed
- IL-4 polarized human macrophage exosomes control cardiometabolic inflammation and diabetes in obesity.
2022 | PubMed
- Visualizing transfer of microbial biomolecules by outer membrane vesicles in microbe-host-communication in vivo.
2021 | PubMed
- High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis.
2021 | PubMed
- M2 macrophage exosomes regulate hematopoiesis & resolve inflammation in atherosclerosis via microrna cargo.
2020 | PubMed
- Abstract 15839: Patients With Abdominal Aortic Aneurysms Have Reduced Levels of MicroRNA 122-5p in Circulating Exosomes.
2020 | PubMed
- Abstract 17293: Hyperglycemia Enhances Pro-Inflammatory Properties of Macrophage-Derived Exosomes to Drive Hematopoiesis in Apolipoprotein E-Deficient Mouse.
2020 | PubMed
- Correction: Cushioned-Density Gradient Ultracentrifugation (C-DGUC) improves the isolation efficiency of extracellular vesicles.
2020 | PubMed
- Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo.
2020 | PubMed
- Circulating exosomes from patients with peripheral artery disease influence vascular cell migration and contain distinct microRNA cargo.
2020 | PubMed
- Abstract C20: Smpd3 augments chemotherapy and thwarts PDA progression.
2019 | PubMed
- Cushioned-Density Gradient Ultracentrifugation (C-DGUC) improves the isolation efficiency of extracellular vesicles.
2019 | PubMed
- Female mice with apolipoprotein E4 domain interaction demonstrated impairments in spatial learning and memory performance and disruption of hippocampal cyto-architecture.
2019 | PubMed
- Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation.
2019 | PubMed
- The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research.
2019 | PubMed
- exRNA Atlas Analysis Reveals Distinct Extracellular RNA Cargo Types and Their Carriers Present across Human Biofluids.
2019 | PubMed
- Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.
2018 | PubMed
- MicroRNA-146a & hematopoiesis: friend or foe in atherosclerosis.
2018 | PubMed
- Apolipoprotein E and Atherosclerosis: From Lipoprotein Metabolism to MicroRNA Control of Inflammation.
2018 | PubMed
- Abstract 184: Hyperglycemia Enhances Pro-inflammatory Properties of Macrophage-derived Exosomes to Drive Hematopoiesis in Apolipoprotein E-deficient Mouse.
2018 | PubMed
- Abstract 262: Circulating Exosomes from PAD Patients Modulate Vascular Repair and Inflammation.
2018 | PubMed
- Abstract 408: ApoE Regulation of Hematopoiesis Suppresses Atherosclerosis by Reducing Adaptive Immunity in Hyperlipidemic Mice.
2018 | PubMed
- Abstract 443: Cushioned-Density Gradient Ultracentrifugation (C-DGUC) Improves the Isolation Efficiency of Exosomes for their use in Atherosclerosis Research.
2018 | PubMed
- Advances, challenges, and opportunities in extracellular RNA biology: insights from the NIH exRNA Strategic Workshop.
2018 | PubMed
- Cushioned-Density Gradient Ultracentrifugation (C-DGUC): A Refined and High Performance Method for the Isolation, Characterization, and Use of Exosomes.
2018 | PubMed
- Isolation of Plasma Lipoproteins as a Source of Extracellular RNA.
2018 | PubMed
- Therapeutic control of systemic inflammation & atherosclerosis with ApoE-polarized macrophage exosomes.
2017 | PubMed
- Hyperpolarized 13 C magnetic resonance evaluation of renal ischemia reperfusion injury in a murine model.
2017 | PubMed
- An intracellular matrix metalloproteinase-2 isoform induces tubular regulated necrosis: implications for acute kidney injury.
2017 | PubMed
- Extending gene ontology in the context of extracellular RNA and vesicle communication.
2016 | PubMed
- Inhibition of p38 Mitogen-Activated Protein Kinase Enhances the Apoptosis Induced by Oxidized Low-Density Lipoprotein in Endothelial Progenitor Cells.
2016 | PubMed
- Immunosuppression With FTY720 Reverses Cardiac Dysfunction in Hypomorphic ApoE Mice Deficient in SR-BI Expression That Survive Myocardial Infarction Caused by Coronary Atherosclerosis.
2016 | PubMed
- Abstract 17311: Molecular Memory and the Epigenetic Regulation of Cardiac Intracellular Matrix Metalloproteinase-2.
2015 | PubMed
- Biogenesis, delivery, and function of extracellular RNA.
2015 | PubMed
- Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium.
2015 | PubMed
- Apolipoprotein e e4 domain interaction in size of hippocampal subregions, density of newborn neurons, and cognitive behaviors.
2015 | PubMed
- Abstract 155: MicroRNA-146a Suppression of NF-?B-driven Monocyte/Macrophage Activation and Atherosclerosis is Regulated by Cellular ApoE Expression.
2015 | PubMed
- Abstract 23: Immunosuppression with FTY720 Reverses Cardiac Dysfunction to Prevent Chronic Heart Failure in Mice that Survive Diet-induced Myocardial Infarction.
2015 | PubMed
- Abstract 481: Diabetic Hyperglycemia Accelerates Atherosclerosis by Driving Adaptive Immunity in Mice with Similar Hyperlipidemia.
2015 | PubMed
- Apolipoprotein E enhances microRNA-146a in monocytes and macrophages to suppress nuclear factor-κB-driven inflammation and atherosclerosis.
2015 | PubMed
- Apolipoprotein E and Atherosclerosis: Beyond Lipid Effects.
2015 | PubMed
- A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver.
2014 | PubMed
- The immunosuppressant FTY720 prolongs survival in a mouse model of diet-induced coronary atherosclerosis and myocardial infarction.
2014 | PubMed
- Hyperglycemia impairs atherosclerosis regression in mice.
2013 | PubMed
- N-terminal truncated intracellular matrix metalloproteinase-2 induces cardiomyocyte hypertrophy, inflammation and systolic heart failure.
2013 | PubMed
- Inducible ApoE gene repair in hypomorphic ApoE mice deficient in the low-density lipoprotein receptor promotes atheroma stabilization with a human-like lipoprotein profile.
2013 | PubMed
- Abstract 195: Apolipoprotein E Suppresses Atherosclerosis by Reducing Th1 Inflammatory Responses and by Favorably Altering Aortic Dendritic Cell Subsets in Hyperlipidemic Mice.
2013 | PubMed
- Abstract 375: Inducible ApoE Gene Repair in HypoE Mice Deficient in the LDL Receptor Promotes Atheroma Stabilization with a Human-like Lipoprotein Profile.
2013 | PubMed
- Abstract 552: The Immunosuppressant FTY720 Increases Longevity and Prevents Chronic Heart Failure in HypoE Mice Deficient in the SR-BI Receptor that Survive Myocardial Infarction Caused by Diet-induced Coronary Atherosclerosis.
2013 | PubMed
- Apolipoprotein E regulation of myeloid cell plasticity in atherosclerosis.
2012 | PubMed
- Macrophage-specific apoE gene repair reduces diet-induced hyperlipidemia and atherosclerosis in hypomorphic Apoe mice.
2012 | PubMed
- A novel intracellular isoform of matrix metalloproteinase-2 induced by oxidative stress activates innate immunity.
2012 | PubMed
- Apolipoprotein E4 domain interaction accelerates diet-induced atherosclerosis in hypomorphic Arg-61 apoe mice.
2012 | PubMed
- ApoE suppresses atherosclerosis by reducing lipid accumulation in circulating monocytes and the expression of inflammatory molecules on monocytes and vascular endothelium.
2011 | PubMed
- Oxidized low-density lipoprotein induces apoptosis in endothelial progenitor cells by inactivating the phosphoinositide 3-kinase/Akt pathway.
2010 | PubMed
- Apolipoprotein E Suppresses Atherosclerosis by Reducing Leukocyte Recruitment to Atheroma.
2010 | PubMed
- Heparin Protects Against Septic Mortality via Apoe-Antagonism.
2010 | PubMed
- High-density lipoprotein determines adult mouse cardiomyocyte fate after hypoxia-reoxygenation through lipoprotein-associated sphingosine 1-phosphate.
2010 | PubMed
- Diet-induced occlusive coronary atherosclerosis, myocardial infarction, cardiac dysfunction, and premature death in scavenger receptor class B type I-deficient, hypomorphic apolipoprotein ER61 mice.
2005 | PubMed
- VEGF is crucial for the hepatic vascular development required for lipoprotein uptake.
2005 | PubMed
- Apolipoprotein E promotes the regression of atherosclerosis independently of lowering plasma cholesterol levels.
2004 | PubMed
- Antibody phenotyping test for the human apolipoprotein E2 isoform.
2003 | PubMed
- Cholesterol: from heart attacks to Alzheimer's disease.
2003 | PubMed
- Hepatocyte-derived ApoE is more effective than non-hepatocyte-derived ApoE in remnant lipoprotein clearance.
2003 | PubMed
- 3P-0878 A mouse model to study the role of ApoE in atherosclerosis regression and plaque vulnerability in peripheral arterial disease.
2003 | PubMed
- Hypomorphic apolipoprotein E mice: a new model of conditional gene repair to examine apolipoprotein E-mediated metabolism.
2002 | PubMed
- Periplasmic expression and purification of recombinant Fabs.
2002 | PubMed
- Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E.
2001 | PubMed
- New insights into the heparan sulfate proteoglycan-binding activity of apolipoprotein E.
2001 | PubMed
- Binding of an antibody mimetic of the human low density lipoprotein receptor to apolipoprotein E is governed through electrostatic forces. Studies using site-directed mutagenesis and molecular modeling.
2000 | PubMed
- Bacterial expression and purification of the Fab fragment of a monoclonal antibody specific for the low-density lipoprotein receptor-binding site of human apolipoprotein E.
1999 | PubMed
- Structure of a monoclonal 2E8 Fab antibody fragment specific for the low-density lipoprotein-receptor binding region of apolipoprotein E refined at 1.9 A.
1999 | PubMed
- Molecular characterization of two monoclonal antibodies specific for the LDL receptor-binding site of human apolipoprotein E.
1995 | PubMed
- Determination of the fine specificity and molecular cloning of two monoclonal antibodies directed against the receptor-binding domain of human apolipoprotein E.
1994 | PubMed